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IB analysis of Smurf1 and Smurf2 in HCT116 cells treated with indicated compounds (1 M, 12 h)
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A mean placebo-adjusted reduction of HbA1c up to 1.2% with the highest dose was also observed [28]
The F1 generation demonstrates 45% sperm count reduction and 38% testosterone decrease, while the F2 generation exhibits persistent sperm motility and morphological abnormalities attributable to heritable DNA methylation changes
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