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Description
The Pentose Phosphate Pathway (PPP) is one of the most significant metabolic pathways for NADPH generation
The helicase Mer3 (HFM1 in humans) is a highly conserved factor essential for promoting crossovers and ensuring their proper distribution
To this end, we expanded the generic human metabolic reconstruction Recon 2.2 19 by incorporating reactions specific to the substrates essential for the replication of the investigated viruses
doi: 10.1002/ana.20687
