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TLK-286: a novel glutathione S-transferase-activated prodrug

Previous studies have demonstrated that curcumin is poorly absorbed by intestinal cells, rapidly metabolized by the liver, and rapidly eliminated from organism (39, 46, 47), Thus, structural characteristics should be considered to improve its bioavailability and enhance its biological activities

Therefore, rifabutin-based treatments have a perspective as a first- or second-line empiric therapy for H

For tyrosinase activity, the cells were lysed in 100 L of 50 mM sodium phosphate buffer (pH 6.5) containing 5 L of 1% Triton X-100 and 5 L of 0.1 mM phenylmethylsulfonylfluoride