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In addition, the activation of the transcription factor Nrf2 in HCECs upregulated AKR1C1 under hyperosmotic conditions
By age 60, the decline reaches 40% or more
After the radical recognition, the detoxification of OH by GSH can take place, the OH is forwarded to CYS.SG and abstracts a hydrogen from this group
Taken together, these data suggest that altered BDNF trafficking contributes to the pathophysiology of MDD
