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Large-scale brewing showed a decline in folate between the end of maturation and the final bottled beer because of operations that do not occur in small-scale brewing, such as filtration, pasteurization, and dilution to the desired gravity with deoxygenated water 302,440,507,508,509,510,511,512,513,514,515
Moreover, the enzyme can be controlled to catalyze hydrolysis, transpeptidation, or autotranspeptidation simply by adjusting reaction pH (Morelli et al., 2014)
