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The inhibition rate goes along with the increased dose of 1D228 and Tepotinib, the IC 50 of 1D228 were 4.3 nM or 1 nM respectively on MHCC97H or MKN45, which is lower than the reference compound Tepotinib which is 13 nM or 1.65 nM
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Klein P, Kaminski RM, Koepp M, Loscher W

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