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Anal Bioanal Chem 407(9):25692579 Wada T, Hosoya T, Honda D, Sakamoto R, Narita K, Sasaki T et al (2018) Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)

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Increased marketing and the voiding of natural antioxidants have supported the market demand significantly

Looking forward, several key research directions warrant urgent investigation: Spatiotemporal Dynamics of mtDNA Damage: Future studies should move beyond bulk tissue to map cell-type specific mtDNA mutations (e.g., exhausted CD8+ T cells vs