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Oxidative stress is a part of many acute and chronic pathological processes in respiratory, cardiovascular, kidney, neurodegenerative, and biliary diseases, as well as in cancer

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Small JV, Rottner K, Kaverina I, Anderson KI

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For instance, in cells for which maintaining redox homeostasis is more important than nucleic acid synthesis, the PPP is tailored to accelerate the oxidative branch and to direct the nonoxidative branch towards re-synthesizing F6P from pentose phosphate, which is then converted back to G6P to replenish the oxidative branch (Fig

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Luger, K., Rechsteiner, T

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