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Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation

ROS also enhance their proliferation via two mechanisms: either by damaging biological molecules, leading to gene mutation and inflammation, or through abnormal oxidative stress redox signaling, which distorts signaling pathways and drives cancer progression

10.1016/j.apt.2013.09.012 28 HonmaneS.HajareA.MoreH.OsmaniR

PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins
