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No evidence of tolerance development (requiring progressively higher doses to achieve the same effect) or physical dependence (withdrawal symptoms upon discontinuation) has been documented in available research, distinguishing DSIP favorably from traditional sleep medications that commonly cause both tolerance and dependence

The only FDA approved therapy for RP is Luxturna (Spark Therapeutics), a subretinal gene therapy to correct RPE65 -induced retinal degeneration
Plasma glutathione peroxidase activity is potentially a key regulator of vascular disease-associated thrombosis
