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Figure 1 Figure 2 To be diagnosed with GWS, the Centers for Disease Control and Prevention (CDC) criteria for Chronic Multisymptomatic Illness (CMI) require symptoms from at least two of the three symptom clusters: general fatigue, mood and cognitive abnormalities, and myalgia/athralgia pain (Fukuda et al., 1998)

insulin resistance contributes to the generation and increasing the secretion of tumor necrosis factor (TNF-), which participates in further consequences of neuropathic pain and degeneration of neurons (Ghouini, Rahal, & Djoghlaf, 2016

The initial suppression could be mediated by increased somatostatin release as pyridostigmine, a postulated inhibitor of somatostatin release, blocks this suppression (502)

Its a pellet implant therapy procedure that only takes a few minutes and with minimal to no downtime
