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However, before iPSCs can advance to clinical trials, several issues need to be addressed, including the correction of mutations, induction of differentiation towards neuronal phenotypes, and ensuring the proliferation and long-term survival of iPSC-derived DA neurons following transplantation

Single-cell RNA sequencing analyses revealed that CR enhances Treg proliferation by altering immune cell metabolism, notably downregulating glycolysis and inflammatory gene expression, and inhibiting the PI3K/AKT/c-Myc signaling pathway

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor