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It is naturally produced in the liver and plays a vital role in detoxifying the body, boosting the immune system, and neutralising free radicals

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2018 Feb 1 [cited

Furthermore, intestinal flora dysfunction is a causative agent of CRC by following mechanisms: 1) Flora with its infiltrating metabolites (including secondary bile acids, H2S and NOCs) promotes inflammation, which influences initiation, promotion and progression of carcinogenesis
