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Such models are used to evaluate receptor activation patterns, biomarker expression, and signaling feedback mechanisms under controlled laboratory conditions, with emphasis on reproducibility and mechanistic interpretation rather than applied outcomes

This is primarily due to the lack of knowledge regarding safe and efficacious dosage levels, a challenge compounded by its low bioavailability (Mazieiro et al., 2018)

doi: 10.1007/s13402-024-00954-6