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glutathione peroxidase 1 does it have iron Frontiers Ferroptosis in Gastrointestinal Diseases: A
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38, D237D243

Iron regulatory proteins (IRPs), bind to iron-responsive elements (IREs) in the 5 untranslated region (UTR) of mRNAs encoding ferritin and FPN1 to inhibit their translation, while binding to IREs in the 3 UTR of TfR1 and DMT1 mRNAs to stabilize these transcripts, thereby adjusting iron storage, export, and uptake (58)

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