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The honest answer is that the evidence base is still developing, which is true of many treatments that are now standard of care, said Dr Anant Vinjamoori, chief medical officer of Hims

However, taking into consideration that Vit B12 deficiency can induce the elevation of Hcy levels, it seems plausible to consider the non-motor aspects related to Hcy (Shipton and Thachil 2015)

Several of the changes observed in connective tissue are thought to reflect variations in the levels of MMPs, the enzymes involved in regulating and maintaining the extracellular matrix that degrade extracellular matrix molecules, proteoglycans, elastin, and different types of collagens [109]

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