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Furthermore, lipoic acid, an antioxidant with anti-inflammatory properties, attenuated oxidative stress and neurotoxicity in SOD1 G93A and SOD1 G85R Drosophila and cell culture models (Moura et al., 2015
Additionally, the Neh2 structural domain contains lysine residues, which are substrates for ubiquitination and are involved in the degradation of the Nrf2 protein [16]
Methylcobalamin is the active, natural form of Vitamin B12
However, redox-sensitive proteins are the most susceptible to ROS and are regarded as ROS potent targets under oxidative stress
