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Third, while bulk proteomics provides a comprehensive view of cellular differentiation pattern, more precise methods such as single-cell technologies (transcriptomics or proteomics) 38,39 and spatiotemporal single-cell tracking 40,41 would further elucidate the detailed cellular composition and 3D organization during iHLO development

"Principles of long-term dynamics of dendritic spines." J Neurosci 28: 13592-608

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