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Int J Biol Sci 8:12541266
Paclobutrazol exposure induces apoptosis and impairs autophagy in hepatocytes via the AMPK/mTOR signaling pathway
Additionally, altered Pantetheine availability due to alteration in Coenzyme A (CoA) metabolism in diabetes 47 , of which pantetheine is an intermediate, might contribute to low PA levels, since even with slightly increased vanin-1 activity, the net production of PA might still be reduced
It reduces melanin production and shifts darker melanin toward lighter forms, which produces a brighter, more even tone
