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Linagliptin also reduces intestinal mucosal oxidative stress by inhibiting lipid peroxides and augmenting GSH, GPX and total antioxidant capacity (132)
Then, the main focus is maintaining vessel function upon the first innate reperfusion (as evidenced by an initial innate recovery while the blood supply is deprived) in IC rats [which is also applicable much later with additional bowel obstruction (IC + OB rats)], and subsequently upon massive reperfusion following the removal of vascular obstruction(s) (IC + RL rats)
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