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10.1155/2013/509130 Can Respir J
Since mitochondrial metabolism is prevalent in normal high-energy-demand tissues, such as the heart and liver, OXPHOS inhibitors (e.g., IACS-010759) have shown dose-limiting toxicities (DLT) in some clinical trials, hindering their widespread application [173]
(A) shows the association of rs713041 genotype (GPX4) with pre-diagnosis erythrocyte GPx (eGPx) activity (Anova, p = 0.015)
S100 and GFAP-immunostained confocal images were stacked and maximally projected for the morphological analysis of astrocytes
