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HPV-16 is the primary causative type, whereas other HPV types including HPV-18, HPV-31, HPV-33 and HPV-52 are also detected in small amounts in HNSCC patients

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This trade-off may be reasonable for individuals with significant healing needs and appropriate risk tolerance, but it should be made consciously rather than by default

While there is no data to establish the safety of 5-amino-1MQ in humans, rodent studies have found no significant adverse effects [1, 6, 11]