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Yeung et al., 2014)
reported accelerated aging with higher expression of the cell cycle inhibitor p21 and cognitive deficits in BMAL1-deficient mice [381]
By manipulating these phases to achieve an optimal balance, it may be possible to sustainably harness mitohormesis as a preventative and therapeutic measure for people at risk of, or suffering with, neurodegenerative disorders
Tan, Z., Scheetz, J
