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Description
Treated animals show increased oxygen consumption and energy expenditure measured by indirect calorimetry, confirming enhanced metabolic rate

These include medically-supervised nutrition plans and folinic acid supplementation

This scoring system allowed for semi-quantitative evaluation of cartilage integrity based on macroscopic features such as softening, fibrillation, erosion, ulceration, and complete cartilage loss [1]

This is not necessarily a sign that AOD-9604 has lost effectiveness, but rather reflects the natural progression of fat loss
