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Garzino-Demo P, Fasolis M, Maggiore GM, Pagano M, Berrone S
Biochemistry and Biophysics Reports, 27, 101107
employed DNPH as a reactive matrix in MALDI-MS to detect peptides modified by 4-hydroxy-2-nonenal (HNE) in undigested samples, achieving the selective detection of modified peptides through the high D/I yield of hydrazone derivatives (Michael adducts with dinitrophenylhydrazine) (Figure )
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