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Figure 20: Photograph of Ivan Lefkovits (left) with his wife and fellow scientist Hana (middle) and Jerne (right), taken at the Paul Ehrlich Institute in Frankfurt (credit: Lefkovits, 1996)

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Dopaminergic transmission is the direct target of a number of drugs of abuse, and is secondarily affected by virtually all abused drugs (reviewed in Volkow and Morales, 2015)

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These are the so-called natural antibodies

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