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doi: 10.1038/s41392-023-01330-w 12 BijlsmaJWBerenbaumFLafeberFPJG

and in older individuals, hypothyroidism accelerates cognitive decline while hyperthyroidism increases anxiety and sleep disturbances ( The thyroidbrain axis represents a complex system of bidirectional communication between endocrine and neural networks

Decreased estrogen signaling triggers increased FSH release from the pituitary gland, and increased FSH signaling increases the chance of ovulation