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doi: 10.1186/1471-2407-8-60 203 GladyshevVNJeangKTWoottonJCHatfieldDL

However, individual dietary strategies should be tailored based on specific patient characteristics and influenced by potentially identifiable individual underlying mechanisms contributing to AF

Based on evidence reviewed in Cristofori et al, SCFAs like butyrate enhance TGF-/Smad3 signaling in B cells, promoting IgA class switching while suppressing IgE production through HDAC inhibition and GATA3 downregulation (129)

Significantly reduce the design lifecycles for critical and complex systems
