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Metabolic dysfunctionassociated steatohepatitis (MASH, formerly nonalcoholic steatohepatitis, NASH) is a major research focus, characterized by excessive hepatic fat accumulation, inflammation, and hepatocellular injury

Physicochemical Properties The isoelectric point (pI) of AOD-9604 is approximately 8.0, reflecting its net positive charge at physiological pH

However, as with any biological therapy, the theoretical possibility of individual hypersensitivity cannot be entirely eliminated, and appropriate monitoring remains prudent

This finding was particularly notable because it occurred despite significant fat loss, demonstrating that the peptides lipolytic effects do not compromise metabolic health