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EVs play multiple roles in EMs, including promoting angiogenesis, modulating inflammation and immune responses, facilitating cell proliferation and inhibiting apoptosis, as well as participating in fibrosis formation ( 3.2.1 EVs affect neurovascular angiogenesis in endometriosis The development and progression of EMs are closely related to neurovascularization (Saunders and Horne, 2021)

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Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that starts with insulin resistance and continues with the abdominal obesity, diabetes mellitus (DM), dyslipidemia, and hypertension [8]

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