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Depletion of this pool in brain mitochondria makes them more vulnerable to toxic effects of H 2 O 2 leading to irreversible damages [45] and death

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Ferroptosis by erastin or RSL3 was inhibited by a more than 20-fold lower concentration of MitoQ, a mitochondrial ROS quencher, compared to DecylQ, a non-targeting counterpart

In summary, glutathione acts as a critical determinant in regulating the inflammatory potential of infiltrating immune cells
