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Stockwell et al., Ferroptosis: An iron-dependent form of nonapoptotic cell death., Cell , 2012 , 149(5), 1060

Under MHRA guidance, peptides supplied by Pure Peptides UK are: Not medicines Not supplements Not intended for human consumption Not supplied with usage instructions All references to milligram quantities are strictly descriptive , not prescriptive

The underlying mechanism involves AS-IVs ability to reduce mitochondrial ROS in myocardial cells of MI mice, inhibit NLRP3 inflammasome activation, and subsequently downregulate the expression of downstream inflammatory factors such as IL-18 and IL-1, along with the caspase-1 regulator involved in cell pyroptosis