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In contrast, while neutrophil numbers were similar between groups before APAP treatment, neutrophil infiltration was significantly increased in FBXL5 CD11c mice compared to controls after APAP treatment (Fig

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The theory proposes that some individuals may have difficulty breaking down lectins, leading to impaired digestion, nutrient absorption, gastrointestinal inflammation, disruption of the gut microbiome, and potentially contributing to leaky gut and systemic inflammation, which could trigger autoimmune issues

Fortunately, treatments can help, including supportive oligonucleotide therapy (also used in cancer treatment), available from the Fairfield Family Health team in Fairfield, Connecticut