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These methods, nevertheless, may have some limitations in detecting mixed infections, as they are designed to identify only the dominant HCV GT in the population and may not detect minor variants 7,19

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These studies have examined the dopaminergic circuit interactions through which MC4R activation produces motivational behaviour changes and have positioned MT-2 as the original reference compound for central melanocortin sexual behaviour research preceding and informing the development of the more MC4R-selective PT-141

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