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Mild restlessness and insomnia have been reported, particularly when taken later in the day [5][7]
Furthermore, the combined therapy was associated with better treatment adherence

watt -1 , respectively Heart rate Heart rate was recorded at rest, during the final 10 seconds of each sprint bout, as well as 4 and 14 minutes post-exercise (see Figure 5)

In the presence of reactive oxygen species, uric acid is metabolized by urate oxidase to allantoin in non-primate mammals [61], and may be considered indicative of increased oxidative stress in ruminants [62]
