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Tesofensine acts most like an appetite control capsule, while AOD-9604 and FTPP lean toward fat metabolism

The evidence suggests AOD9604 may be especially effective at reducing visceral adipose tissue, which is strongly linked with metabolic disease risk and cardiovascular complications

Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014 Apr 10;508(7495):258-62. doi: 10.1038/nature13198. PMID: 24717514; PMCID: PMC4107212

The question is whether adding AOD 9604 justifies the additional cost, injection frequency, and complexity