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However, inflammatory activation of iNOS by cytokines or lipopolysaccharides enhances cellular levels of NO and results in inflammatory diseases and septic shock (38)

Furthermore, studies have shown that high-fat diet levels can affect the architecture of brain cell tissues, promote iron accumulation, limit the activity of endogenous antioxidant mechanisms, and may induce ferroptosis in cells (Chang et al., 2023)
Furthermore, vitamin E has also several protein dependent functions and gene modulation effects in inflammation

Although these treatments have been shown to be effective, very little thought is put into the mechanisms by which these so-called neurotransmitter imbalances occur
