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Typically, these unstable molecules are kept in check by the second type of molecule antioxidants

Consequently, the authors propose that A1AT augmentation therapy should be considered and investigated as a potential treatment for COVID-19

Indeed, among other effects, elevated homocysteine levels could alter arterial reactivity to adrenergic stimulation, modifying vascular sensitivity to norepinephrine, thus prompting vasorelaxation (Cipolla et al

Of note are the preferential distributions of the transsulfuration pathway and the catabolizing enzyme glycine N-methyltransferase in mammalian tissues such as liver and kidney (Finkelstein, 1990)
