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82002306), the Chongqing Science & Technology Commission (No

& Felsher, D
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Irisin also significantly alleviates tubular epithelial cell injury and fibrosis by inhibiting Smad3 phosphorylation and suppressing the expression of Nox4 (a downstream regulator of ferroptosis) in the UUO mouse model, thus blocking Smad3-mediated ferroptosis (202)

Keywords: lutein, zeaxanthin, xanthophylls, carotenoid deficiency, age-related macular degeneration, oxidative stress 1
