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Description
In the cytosol, several metabolic pathways lead to its formation, namely, glycolysis, the oxidation of lactate, the reaction catalyzed by the cytosolic malic enzyme, and the catabolism of at least six amino acids, the most important of which is alanine
Damage usually occurs in hepatic zone III as oxidative metabolism is concentrated in this area
It may be possible to answer this question by analyzing what makes animals with similar genetic vulnerabilities different
doi: 10.1016/0005-2760(93)90052-b [DOI] [PubMed] [Google Scholar] 5
