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Deficiency in vitamin B6 is commonly linked to malnutrition, alcoholism, malabsorption syndromes, or as an adverse effect of certain medications, such as cyclosporine, hydralazine, cycloserine, penicillamine, isoniazid, levodopa, phenelzine and chemotherapy treatments (, , , )

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Therefore, the goal of determining solvation in water of a broad range of solutes has been made simpler using the companion ideas of model-compound partitioning and additivity relationships

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