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Description
(1998) identified the first GPCR heterodimer and described it as an obligate heterodimer, consisting of the complex formed by a GABA B R1 and a GABA B R2 protomer (Jones et al., 1998

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doi: 10.1111/j.1574-6976.2008.00127.x 18 PengH.YinH.DengJ.YeJ.-S.ChenS.-N.HeB.-Y.et al

Treatment involves dietary optimisation, oral supplementation for mild deficiency, or intramuscular hydroxocobalamin injections for significant deficiency or neurological involvement
