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Description
Transcription factor hDREF is a novel SUMO E3 ligase of Mi2*
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The emergence of predominantly cognitive FTD-like phenotypes in the TDP-43 K408R mice is not unusual in TDP-43 knock in models such as TDP-43 Q331K and TDP-43 K145R mice which present with features of cognitive dysfunction but lacking the entire constellation of ALS/FTD-like phenotypes[45, 119]
