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Neurodegeneration by oxidative stress: a review on prospective use of small molecules for neuroprotection
For example, increases in synaptic strength following repeated cocaine exposure trigger homeostatic changes in membrane excitability in MSNs in the NAc, which appear to contribute to incubation of cocaine craving (349)
These factors could become self-perpetuating as more oxidative stress is generated by the inflammatory responses, promoting persistence of disease
