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Hepatocytes, myocytes, and brown adipocytes are characterized by particularly high metabolic activity (Frayn et al., 2006), as adipose, skeletal muscle, and particularly liver are among the top contributors to whole-body basal metabolic activity (Wang et al., 2012)

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Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment

Am J Physiol Endocrinol Metab 320(4):E732E746 Huang C et al (2021) Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway
