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Category 1 reclassification restores legal compounding access but does not represent the same level of scientific validation as FDA approval

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Prostaglandin causes vasospasm of the spiral arterioles, and subsequent ischemia and sloughing of the endometrium is what patients experience as a "periods.' The uterine cramping associated with the normal ovulatory cycle is caused by this prostaglandin's action and explains the effectiveness of prostaglandin inhibitors (aspirin or ibuprofen) in the treatment of dysmenorrhea

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