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Confirming previous observations, another study using the EPIC array found no DMP in a large cohort [70]

Eur J Med Chem 98:203211 Iqbal J, El-Gamal MI, Ejaz SA, Lecka J, Sevigny J, Ohg CH (2018) Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies

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There was an interaction between treatment and experimental time on plasma urea concentrations (P=0.05, Figure 4 ), and it was observed that the values among treatments were very close at the beginning of the experiment and 40 days of supplementation, but there was a difference at 60 days when animals supplemented with SeVitEFe showed a lower concentration compared to control animals