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Description
Patients experience cough, mucus hypersecretion, wheezing, chest tightness, and breathing difficulty, especially during physical activities [11]

Thus, the combination of TLR9 stimulation and PD-1 blockade reshapes macrophages into a more suppressive, tumor-promoting state, limiting the potential therapeutic benefit of this regimen in ovarian cancer (156)

Removal by natural or artificial mutation of this arginine residue completely abolishes glutamine feedback inhibition in these GS homologue similar to the Bacillus subtilis GS homologue

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