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Understanding this process is essential for researching TMAOs physiological roles and regulating its levels

The peak levels rose in a dose-dependent manner within approximately 2.5 hours, and the pharmacological effects persisted for about six hours
For example, chronic intermittent alcohol exposure significantly increased I A in NAc medium spiny neurons (Marty and Spigelman, 2012) and decreased I A in hippocampal CA1 interneurons (Li et al., 2013)

This is more likely related to underlying medical conditions or interactions with other medications
