glutathione peroxidase enzyme system 4: a new player in neurodegeneration? Glutathione peroxidase - Wikipedia
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It is thought that high-risk variants cause APOL1-mediated kidney disease in a way that is very similar to how it causes cytotoxicity in laboratory animals

Shankar J, Geetha KM, Wilson B

In the first step, NADPH binds to the FAD ox -Fd III ox complex

10.1038/414863a 32 CryanJ
